Global Mice Model Industry Overview Size, Share, Trends, Growth(2024

The global mice model market was estimated to be worth USD 1,217.90 million in 2023 and is expected to grow to USD 2,475.50 million by the end of 2032, per a research released by Zion Market Research. Over the course of the projected period, the market is anticipated to expand at a CAGR of 8.20%. The growth factors, barriers, and effects on demand of the worldwide mice model market are examined in this study for the period of forecasting. Additionally, it will assist in navigating and investigating the emerging opportunities in the Mice Model Market sector.

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Introduction

The mice model market plays a critical role in biomedical research, drug discovery, and preclinical testing. Mice models, especially genetically engineered ones, are invaluable for studying human diseases, understanding genetic functions, and testing potential treatments. With advancements in gene-editing technologies and increased investment in pharmaceutical research, the global mice model market has witnessed steady growth. This article delves into the current trends, growth drivers, emerging challenges, and future prospects of the mice model market.

Overview of the Worldwide Mice Model Market

The global mice model market is projected to grow at a robust compound annual growth rate (CAGR) of 6–8% from 2023 to 2030. This growth is driven by the rising demand for animal models in biomedical research, the growing prevalence of chronic diseases such as cancer and diabetes, and increasing investments in drug discovery and personalized medicine. The market can be segmented based on model type, application, and region.

The mouse is a common model system because it is an animal with highly significant genetic resources and advanced genetic tools. In order to investigate human pathophysiology and illness progression, mice are the most suitable model. Reconstituted human tissues and cells are being used to create new models. Since humans share the majority of their DNA, new avenues for genetic testing are becoming available.

Mice Model Market Segmentation Worldwide

The market for mouse models is divided into four segments on a global scale: type, technology, application, and service. Genetically altered mice, hybrid/congenic mice, spontaneous mutant mice, inbred mice, conditioned/surgically modified mice, and outbred mice are the several types of mice that make up the global mouse model market. Microinjection, nuclear transfer, genetically modified sperm-mediated gene transfer, electroporation of DNA & liposome-mediated DNA, CRISPR, embryonic stem cell injection, virus/vector-mediated gene transfer, biolistics & TALENs & ZFN are the different technology-based market segments. Studies on immunology and inflammation, cardiovascular disease, uncommon diseases, toxicity, cancer, diabetes, the central nervous system, renal problems, haematopoiesis, and other topics are among the many applications that use the mouse model. Cryopreservation, rederivation model in licensing, surgery, in vivo pharmacology services, breeding services, quarantine, genetic testing, and line rescue are the service-based segments of the market.

Growth Factors for the Global Mice Model Market

Both the growing need for tailored medications and the continuous advancements in mouse models are significant drivers driving the market’s expansion. The market for mouse models is expected to grow in the upcoming years due to an increase in pharmaceutical research and development activities. Furthermore, mice are employed as models for rare illness research, which raises the demand for the product on the international market. The manufacture of monoclonal antibodies has increased, which is helping the global market for mouse models grow overall.

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Market for Mice Models: Report Scope

Regional Analysis of the Global Mice Model Market

The global market for mouse models is divided into several areas, including North America, Asia-Pacific, Europe, and the rest of the world. North America is the market leader for mice models worldwide. Due to the existence of sizable pharmaceutical industries in the North American region as well as the extensive R&D being conducted there, this dominance is expected to persist in the years to come. The second-largest market in the world is in Europe. The Asia-Pacific mice model market is growing as a result of rising demand for knockout and transgenic mouse models. The nations of China, Malaysia, India, and Singapore are the main contributors to the industry expansion.

Key Segments of the Mice Model Market:

By Model Type:
By Application:
By End-User:

Key Growth Drivers

Several factors are propelling the growth of the mice model market:

Rising Prevalence of Chronic Diseases: The growing incidence of diseases such as cancer, diabetes, and cardiovascular disorders has accelerated the demand for animal models to develop and test new treatments. Mice, due to their genetic similarity to humans and ease of manipulation, are the preferred choice for such research.
Advancements in Gene-Editing Technologies: Innovations in technologies like CRISPR/Cas9 have enabled the creation of precise genetically engineered mice models. These models allow researchers to mimic human disease conditions more accurately, leading to better drug discovery outcomes and personalized medicine approaches.
Increasing Investment in Biomedical Research: Governments and private organizations are pouring more resources into life sciences research, particularly in the fields of cancer, rare diseases, and regenerative medicine. This has spurred demand for mice models to facilitate basic and translational research.
Expansion of Contract Research Organizations (CROs): The rise of CROs providing animal model services has made it easier for pharmaceutical and biotech companies to outsource research, further boosting the mice model market. These organizations offer custom mouse model generation, breeding, and phenotyping services, reducing the burden on in-house research teams.
Regulatory Support for Animal Models in Preclinical Studies: Regulatory agencies such as the FDA continue to emphasize the importance of animal models in preclinical safety and efficacy testing of new drugs. The use of mice models in toxicology studies remains a cornerstone for bringing therapies to market.

Emerging Trends

Humanized Mice Models: Humanized mice, which are engineered to carry human genes, tissues, or immune cells, are gaining traction. These models are particularly useful in studying immune system responses, infectious diseases, and cancer immunotherapy.
Personalized Medicine and Precision Research: The trend towards personalized medicine has led to a demand for patient-derived xenograft (PDX) models, where human tumor samples are implanted in mice. This approach allows for the study of individual patient responses to treatments, advancing precision oncology.
3D Bioprinting and Organoid Integration: Mice models are increasingly being used in conjunction with advanced technologies like 3D bioprinting and organoid research. These integrated systems enhance the ability to simulate human organ responses and reduce the limitations associated with traditional mice models.
Increased Focus on Rare Diseases: The mice model market is seeing growing demand from research focusing on rare and genetic disorders. As rare disease research accelerates, researchers require sophisticated mouse models to study disease mechanisms and test experimental therapies.
Ethical and Alternative Research Models: Although the demand for mice models is strong, there is a growing ethical push for reducing animal use in research. This has led to developments in alternative methods like in vitro studies, organ-on-chip technology, and AI-driven simulations. However, animal models, especially mice, remain essential for complex biological processes that cannot be replicated otherwise.

Challenges

While the mice model market is expanding, it faces several challenges:

Ethical Concerns and Animal Welfare Regulations: Increasing scrutiny from animal rights groups and stringent animal welfare regulations are putting pressure on researchers to minimize the use of animals in experimentation. The need for ethical compliance can complicate research protocols and increase costs.
High Costs of Genetically Engineered Models: Developing genetically engineered mice models, particularly those that mimic human diseases, can be expensive and time-consuming. Custom models may require extensive breeding programs and genetic validation, leading to increased research costs.
Limitations in Disease Translation: While mice are biologically similar to humans, there are significant differences in disease progression and drug response. This gap sometimes leads to poor translatability of results from mice models to human clinical outcomes, which can limit their effectiveness in certain research areas.
Alternatives to Animal Testing: The rise of in vitro testing, computational modeling, and other non-animal research methods presents a challenge to the growth of the animal model market. Regulatory bodies are encouraging the use of alternatives where possible, pushing researchers to develop non-animal testing methods.

Competitive Landscape

The mice model market is highly competitive, with several key players leading the industry. Major companies in the space include:

Charles River Laboratories International, Inc.
The Jackson Laboratory
Taconic Biosciences
Envigo
Horizon Discovery Group
Genoway
Crown Bioscience, Inc.

These companies offer a range of services, including the development of custom genetically engineered mice models, breeding services, phenotyping, and preclinical testing.

Future Outlook

The future of the mice model market looks promising, driven by increasing research in disease modeling, gene therapy, and drug discovery. The growth of personalized medicine, advancements in gene editing, and rising global healthcare needs will continue to fuel demand for sophisticated animal models.

In terms of regional growth, North America is expected to remain the dominant market, thanks to its strong research infrastructure and high investment in pharmaceutical R&D. However, the Asia-Pacific region is expected to witness the highest growth, driven by expanding biomedical research initiatives and the rise of contract research organizations.

Conclusion

The mice model market is a crucial component of biomedical research, offering invaluable tools for studying human diseases and developing new therapies. While challenges such as ethical concerns and the rise of alternative methods may affect market dynamics, the continued demand for genetically engineered models, coupled with advancements in research technologies, will sustain growth in the coming years. As the industry evolves, companies that focus on innovation, precision, and ethical research practices will remain at the forefront of this expanding market.

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